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non contact inkjet microarray printer  (SCIENION)


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    SCIENION non contact inkjet microarray printer
    The VANC-D4 assay (A) Fabrication of the VANC-D4 assay. SI-ATRP is used to grow POEGMA-co-GMA brushes on glass slides. Following SI-ATRP, VANC-BSA is <t>inkjet</t> printed into the polymer brush to create stable spots and fluorescently labeled anti-VANC antibodies (termed dAb) are printed on trehalose pads to create labile spots. (B) Sequential steps of the VANC-D4 assay. The steps of the VANC-D4 are (i) dispensing a blood sample on the surface, (ii) dissolution of the trehalose pads to release the fluorescently labeled dAb into solution, (iii) diffusion of the labeled dAb in the sample volume, (iv) detection of fluorescence signal from the antibody bound to immobilized VANC-BSA. (C) Representative VANC-D4 assay response in the presence of (i) no drug, (ii) low drug, and (iii) high drug concentration. (D) VANC monitoring across its clinical range using VANC-spiked whole blood diluted 100-fold in running buffer, analyzed in triplicate. The clinical range for the test is 1–45 μg/mL. Intensity values are shown, with error bars that represent the standard error of the means for n = 3 separate runs. The LOD for the presented dose-response curve was calculated to be 0.8 μg/mL.
    Non Contact Inkjet Microarray Printer, supplied by SCIENION, used in various techniques. Bioz Stars score: 95/100, based on 77 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/contact+microarray+printer/sciFLEXARRAYER+S12/pmc13380757-243-19-23
    Average 95 stars, based on 77 article reviews
    non contact inkjet microarray printer - by Bioz Stars, 2026-10
    95/100 stars

    Images

    1) Product Images from "A rapid point-of-care test for vancomycin monitoring at the clinical bedside"

    Article Title: A rapid point-of-care test for vancomycin monitoring at the clinical bedside

    Journal: iScience

    doi: 10.1016/j.isci.2026.116064

    The VANC-D4 assay (A) Fabrication of the VANC-D4 assay. SI-ATRP is used to grow POEGMA-co-GMA brushes on glass slides. Following SI-ATRP, VANC-BSA is inkjet printed into the polymer brush to create stable spots and fluorescently labeled anti-VANC antibodies (termed dAb) are printed on trehalose pads to create labile spots. (B) Sequential steps of the VANC-D4 assay. The steps of the VANC-D4 are (i) dispensing a blood sample on the surface, (ii) dissolution of the trehalose pads to release the fluorescently labeled dAb into solution, (iii) diffusion of the labeled dAb in the sample volume, (iv) detection of fluorescence signal from the antibody bound to immobilized VANC-BSA. (C) Representative VANC-D4 assay response in the presence of (i) no drug, (ii) low drug, and (iii) high drug concentration. (D) VANC monitoring across its clinical range using VANC-spiked whole blood diluted 100-fold in running buffer, analyzed in triplicate. The clinical range for the test is 1–45 μg/mL. Intensity values are shown, with error bars that represent the standard error of the means for n = 3 separate runs. The LOD for the presented dose-response curve was calculated to be 0.8 μg/mL.
    Figure Legend Snippet: The VANC-D4 assay (A) Fabrication of the VANC-D4 assay. SI-ATRP is used to grow POEGMA-co-GMA brushes on glass slides. Following SI-ATRP, VANC-BSA is inkjet printed into the polymer brush to create stable spots and fluorescently labeled anti-VANC antibodies (termed dAb) are printed on trehalose pads to create labile spots. (B) Sequential steps of the VANC-D4 assay. The steps of the VANC-D4 are (i) dispensing a blood sample on the surface, (ii) dissolution of the trehalose pads to release the fluorescently labeled dAb into solution, (iii) diffusion of the labeled dAb in the sample volume, (iv) detection of fluorescence signal from the antibody bound to immobilized VANC-BSA. (C) Representative VANC-D4 assay response in the presence of (i) no drug, (ii) low drug, and (iii) high drug concentration. (D) VANC monitoring across its clinical range using VANC-spiked whole blood diluted 100-fold in running buffer, analyzed in triplicate. The clinical range for the test is 1–45 μg/mL. Intensity values are shown, with error bars that represent the standard error of the means for n = 3 separate runs. The LOD for the presented dose-response curve was calculated to be 0.8 μg/mL.

    Techniques Used: Polymer, Labeling, Dissolution, Diffusion-based Assay, Fluorescence, Concentration Assay

    Related Articles

    Microarray:

    Article Title: Asymmetrical Biantennary Glycans Prepared by a Stop-and-Go Strategy Reveal Receptor Binding Evolution of Human Influenza A Viruses
    Article Snippet: Control lectins Erythrina cristagalli agglutinin (ECA) [Cat#B1145], Sambuca nigra agglutinin (SNA) [Cat# B-1305], and Maackia amurensis lectin I (MAL-I) [Cat# B-1315] were purchased from Vector Labs. 3.2 Glycan printing surfaces Compounds were printed on amine reactive, N-hydroxy succinimide (NHS)-activated glass slides (NEXTERION ® Slide H, Schott Inc) employing the free amine of the anomeric asparagine moiety of the N-glycans for immobilization. .. The printing was performed using a Scienion sciFLEXARRAYER S3 non-contact microarray printer equipped with a Scienion PDC80 nozzle (Scienion Inc). ..

    Article Title: Sialic acid O -acetylation patterns and glycosidic linkage type determination by ion mobility-mass spectrometry
    Article Snippet: Printing Surface; e.g., Microarray Slide Description of surface Streptavidin-coated glass slides (SuperStreptavidin Microarray Substrate Slides) Manufacturer ArrayIt Inc Covalent Immobilization - 4. .. Arrayer (Printer) Description of Arrayer Non-contact microarray printer, sciFLEXARRAYER S3, Scienion Inc. Dispensing mechanism Non-contact, one nozzle Glycan deposition 400 pL of 100 μM, 40 fmol, 6 replicates Printing conditions 100 μM printing concentration, 20 °C, 50% humidity, blocking with TMS binding buffer (20 mM TRIS·HCl, pH 7, 150 mM NaCl, 2mM CaCl2, 2 mM MgCl2, 0.05% Tween-20 and 1% BSA) for 1 h at 4 °C prior to use. ..

    Article Title: A rapid point-of-care test for vancomycin monitoring at the clinical bedside
    Article Snippet: Woollam alpha 2.0 spectroscopic ellipsometer, and by X-ray photoelectron spectroscopy (XPS) on a ThermoFisher Scientific Nexsa G2 surface analyzer (Catalog Number: 9961253). .. Following polymerization, D4 assays were fabricated using non-contact inkjet printing methods as described elsewhere., VANC-BSA was printed using a non-contact inkjet microarray printer (Scienion, sciFLEXARRAYER Type S12). ..

    Article Title: Asymmetrical Bi-antennary Glycans Prepared by a Stop-and-Go Strategy Reveal Receptor Binding Evolution of Human Influenza A Viruses
    Article Snippet: Control lectins Erythrina cristagalli agglutinin (ECA) [Cat#B1145], Sambuca nigra agglutinin (SNA) [Cat# B-1305], and Maackia amurensis lectin I (MAL-I) [Cat# B-1315] were purchased from Vector Labs. 3.2 Glycan printing surfaces Compounds were printed on amine reactive, N-hydroxy succinimide (NHS)-activated glass slides (NEXTERION ® Slide H, Schott Inc) employing the free amine of the anomeric asparagine moiety of the N-glycans for immobilization. .. The printing was performed using a Scienion sciFLEXARRAYER S3 non-contact microarray printer equipped with a Scienion PDC80 nozzle (Scienion Inc). ..

    Article Title: Revealing the Specificity of Human H1 Influenza A Viruses to Complex N -Glycans
    Article Snippet: Printing Surface; e.g., Microarray Slide Description of surface NHS-activated glass (NEXTERION ® Slide H,) Manufacturer Schott Inc. Covalent Immobilization NHS-ester for amine functional groups (reacting with terminal Asn) 4. .. Arrayer (Printer) Description of Arrayer Non-contact microarray printer, sciFLEXARRAYER S3, Scienion Inc. Dispensing mechanism Non-contact, one nozzle Glycan deposition 400 pL of 100 μM, 40 fmol, 6 replicates Printing conditions 100 μM printing concentration, 20 °C, 50% humidity, blocking with 5 mM ethanolamine in TRIS buffer (pH 9, 100 mM) for 1 h at 50 °C. ..

    Article Title: A point-of-care test to measure tacrolimus directly from unprocessed whole blood
    Article Snippet: Specifically, a dAb cocktail of Alexa Fluor 647-labeled anti-tacrolimus (Creative Diagnostics Catalog Number: DPABH-29477), anti-IL-6 (R&D Systems Catalog Number: AF-206), and anti-MMP3 (R&D Systems Catalog Number: AF513) were printed at 0.02, 0.05, and 0.05 mg/mL respectively with the same BioDot AD1520 Aspirate Dispense System on trehalose pads on slides coated with POEGMA-co-GMA brushes. .. Following dAb printing, TAC-BSA (Creative Diagnostics Catalog Number: DAGA-190B), anti-IL-6 cAbs (R&D Systems Catalog Number: MAB206), and anti-MMP3 cAbs (R&D Systems Catalog Number: AF513) were printed using the Scienion non-contact inkjet microarray printer (Scienion, sciFLEXARRAYER Type S12). .. Purified recombinant human IL-6 (R&D Systems Catalog Number: 206-IL) and MMP3 (R&D Systems Catalog Number: 513-MP) were spiked into fetal bovine serum (Sigma Aldrich Catalog Number: F4135).

    Glycoproteomics:

    Article Title: Sialic acid O -acetylation patterns and glycosidic linkage type determination by ion mobility-mass spectrometry
    Article Snippet: Printing Surface; e.g., Microarray Slide Description of surface Streptavidin-coated glass slides (SuperStreptavidin Microarray Substrate Slides) Manufacturer ArrayIt Inc Covalent Immobilization - 4. .. Arrayer (Printer) Description of Arrayer Non-contact microarray printer, sciFLEXARRAYER S3, Scienion Inc. Dispensing mechanism Non-contact, one nozzle Glycan deposition 400 pL of 100 μM, 40 fmol, 6 replicates Printing conditions 100 μM printing concentration, 20 °C, 50% humidity, blocking with TMS binding buffer (20 mM TRIS·HCl, pH 7, 150 mM NaCl, 2mM CaCl2, 2 mM MgCl2, 0.05% Tween-20 and 1% BSA) for 1 h at 4 °C prior to use. ..

    Article Title: Revealing the Specificity of Human H1 Influenza A Viruses to Complex N -Glycans
    Article Snippet: Printing Surface; e.g., Microarray Slide Description of surface NHS-activated glass (NEXTERION ® Slide H,) Manufacturer Schott Inc. Covalent Immobilization NHS-ester for amine functional groups (reacting with terminal Asn) 4. .. Arrayer (Printer) Description of Arrayer Non-contact microarray printer, sciFLEXARRAYER S3, Scienion Inc. Dispensing mechanism Non-contact, one nozzle Glycan deposition 400 pL of 100 μM, 40 fmol, 6 replicates Printing conditions 100 μM printing concentration, 20 °C, 50% humidity, blocking with 5 mM ethanolamine in TRIS buffer (pH 9, 100 mM) for 1 h at 50 °C. ..

    Concentration Assay:

    Article Title: Sialic acid O -acetylation patterns and glycosidic linkage type determination by ion mobility-mass spectrometry
    Article Snippet: Printing Surface; e.g., Microarray Slide Description of surface Streptavidin-coated glass slides (SuperStreptavidin Microarray Substrate Slides) Manufacturer ArrayIt Inc Covalent Immobilization - 4. .. Arrayer (Printer) Description of Arrayer Non-contact microarray printer, sciFLEXARRAYER S3, Scienion Inc. Dispensing mechanism Non-contact, one nozzle Glycan deposition 400 pL of 100 μM, 40 fmol, 6 replicates Printing conditions 100 μM printing concentration, 20 °C, 50% humidity, blocking with TMS binding buffer (20 mM TRIS·HCl, pH 7, 150 mM NaCl, 2mM CaCl2, 2 mM MgCl2, 0.05% Tween-20 and 1% BSA) for 1 h at 4 °C prior to use. ..

    Article Title: Revealing the Specificity of Human H1 Influenza A Viruses to Complex N -Glycans
    Article Snippet: Printing Surface; e.g., Microarray Slide Description of surface NHS-activated glass (NEXTERION ® Slide H,) Manufacturer Schott Inc. Covalent Immobilization NHS-ester for amine functional groups (reacting with terminal Asn) 4. .. Arrayer (Printer) Description of Arrayer Non-contact microarray printer, sciFLEXARRAYER S3, Scienion Inc. Dispensing mechanism Non-contact, one nozzle Glycan deposition 400 pL of 100 μM, 40 fmol, 6 replicates Printing conditions 100 μM printing concentration, 20 °C, 50% humidity, blocking with 5 mM ethanolamine in TRIS buffer (pH 9, 100 mM) for 1 h at 50 °C. ..

    Blocking Assay:

    Article Title: Sialic acid O -acetylation patterns and glycosidic linkage type determination by ion mobility-mass spectrometry
    Article Snippet: Printing Surface; e.g., Microarray Slide Description of surface Streptavidin-coated glass slides (SuperStreptavidin Microarray Substrate Slides) Manufacturer ArrayIt Inc Covalent Immobilization - 4. .. Arrayer (Printer) Description of Arrayer Non-contact microarray printer, sciFLEXARRAYER S3, Scienion Inc. Dispensing mechanism Non-contact, one nozzle Glycan deposition 400 pL of 100 μM, 40 fmol, 6 replicates Printing conditions 100 μM printing concentration, 20 °C, 50% humidity, blocking with TMS binding buffer (20 mM TRIS·HCl, pH 7, 150 mM NaCl, 2mM CaCl2, 2 mM MgCl2, 0.05% Tween-20 and 1% BSA) for 1 h at 4 °C prior to use. ..

    Article Title: Revealing the Specificity of Human H1 Influenza A Viruses to Complex N -Glycans
    Article Snippet: Printing Surface; e.g., Microarray Slide Description of surface NHS-activated glass (NEXTERION ® Slide H,) Manufacturer Schott Inc. Covalent Immobilization NHS-ester for amine functional groups (reacting with terminal Asn) 4. .. Arrayer (Printer) Description of Arrayer Non-contact microarray printer, sciFLEXARRAYER S3, Scienion Inc. Dispensing mechanism Non-contact, one nozzle Glycan deposition 400 pL of 100 μM, 40 fmol, 6 replicates Printing conditions 100 μM printing concentration, 20 °C, 50% humidity, blocking with 5 mM ethanolamine in TRIS buffer (pH 9, 100 mM) for 1 h at 50 °C. ..

    Binding Assay:

    Article Title: Sialic acid O -acetylation patterns and glycosidic linkage type determination by ion mobility-mass spectrometry
    Article Snippet: Printing Surface; e.g., Microarray Slide Description of surface Streptavidin-coated glass slides (SuperStreptavidin Microarray Substrate Slides) Manufacturer ArrayIt Inc Covalent Immobilization - 4. .. Arrayer (Printer) Description of Arrayer Non-contact microarray printer, sciFLEXARRAYER S3, Scienion Inc. Dispensing mechanism Non-contact, one nozzle Glycan deposition 400 pL of 100 μM, 40 fmol, 6 replicates Printing conditions 100 μM printing concentration, 20 °C, 50% humidity, blocking with TMS binding buffer (20 mM TRIS·HCl, pH 7, 150 mM NaCl, 2mM CaCl2, 2 mM MgCl2, 0.05% Tween-20 and 1% BSA) for 1 h at 4 °C prior to use. ..

    other:

    Article Title: Enzyme-Sialylation-Controlled Chemical Sulfation of Glycan Epitopes for Decoding the Binding of Siglec Ligands
    Article Snippet: 66 amine-linked glycans were printed using a Scienion sciFLEXARRAYER S1 non-contact microarray printer equipped with a Scienion PDC80 nozzle (Scienion Inc) on the surface of N-hydroxy succinimide (NHS)-activated glass slides (NEXTERION Slide H, Schott Inc) to form glycan microarray.

    Article Title: A Bioactive Synthetic Outer-Core Oligosaccharide Derived from a Klebsiella pneumonia Lipopolysaccharide for Bacteria Recognition.
    Article Snippet: There is an urgent need for new treatment options for carbapenem-resistant Klebsiella pneumoniae (K. pneumoniae), which is a common cause of life-threatening hospitaland community-acquired infections.. Prophylactic or therapeutic vaccination may offer an approach to control these infections, however, none has yet been approved for human use.. Here, we report the chemical synthesis of an outer core tetraand pentasaccharide derived from the lipopolysaccharide of K. pneumoniae.



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    Image Search Results


    The VANC-D4 assay (A) Fabrication of the VANC-D4 assay. SI-ATRP is used to grow POEGMA-co-GMA brushes on glass slides. Following SI-ATRP, VANC-BSA is inkjet printed into the polymer brush to create stable spots and fluorescently labeled anti-VANC antibodies (termed dAb) are printed on trehalose pads to create labile spots. (B) Sequential steps of the VANC-D4 assay. The steps of the VANC-D4 are (i) dispensing a blood sample on the surface, (ii) dissolution of the trehalose pads to release the fluorescently labeled dAb into solution, (iii) diffusion of the labeled dAb in the sample volume, (iv) detection of fluorescence signal from the antibody bound to immobilized VANC-BSA. (C) Representative VANC-D4 assay response in the presence of (i) no drug, (ii) low drug, and (iii) high drug concentration. (D) VANC monitoring across its clinical range using VANC-spiked whole blood diluted 100-fold in running buffer, analyzed in triplicate. The clinical range for the test is 1–45 μg/mL. Intensity values are shown, with error bars that represent the standard error of the means for n = 3 separate runs. The LOD for the presented dose-response curve was calculated to be 0.8 μg/mL.

    Journal: iScience

    Article Title: A rapid point-of-care test for vancomycin monitoring at the clinical bedside

    doi: 10.1016/j.isci.2026.116064

    Figure Lengend Snippet: The VANC-D4 assay (A) Fabrication of the VANC-D4 assay. SI-ATRP is used to grow POEGMA-co-GMA brushes on glass slides. Following SI-ATRP, VANC-BSA is inkjet printed into the polymer brush to create stable spots and fluorescently labeled anti-VANC antibodies (termed dAb) are printed on trehalose pads to create labile spots. (B) Sequential steps of the VANC-D4 assay. The steps of the VANC-D4 are (i) dispensing a blood sample on the surface, (ii) dissolution of the trehalose pads to release the fluorescently labeled dAb into solution, (iii) diffusion of the labeled dAb in the sample volume, (iv) detection of fluorescence signal from the antibody bound to immobilized VANC-BSA. (C) Representative VANC-D4 assay response in the presence of (i) no drug, (ii) low drug, and (iii) high drug concentration. (D) VANC monitoring across its clinical range using VANC-spiked whole blood diluted 100-fold in running buffer, analyzed in triplicate. The clinical range for the test is 1–45 μg/mL. Intensity values are shown, with error bars that represent the standard error of the means for n = 3 separate runs. The LOD for the presented dose-response curve was calculated to be 0.8 μg/mL.

    Article Snippet: Following polymerization, D4 assays were fabricated using non-contact inkjet printing methods as described elsewhere., VANC-BSA was printed using a non-contact inkjet microarray printer (Scienion, sciFLEXARRAYER Type S12).

    Techniques: Polymer, Labeling, Dissolution, Diffusion-based Assay, Fluorescence, Concentration Assay